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Mathematical modeling of neuronal connexin-36 channels
Cita
Jaimes-Reátegui, Rider, Barrio, Luis C., González Nieto, Daniel 
ORCID: https://orcid.org/0000-0003-2972-729X and Pisarchik, Alexander ORCID: https://orcid.org/0000-0003-2471-2507
(2015).
Mathematical modeling of neuronal connexin-36 channels.
En: "BBVA Workshop on recent advances in bioinformatics and neuroscience", 09/06/2015 - 11/06/2015, MADRID, SPAIN. p. 1.
ORCID: https://orcid.org/0000-0003-2972-729X and Pisarchik, Alexander ORCID: https://orcid.org/0000-0003-2471-2507
(2015).
Mathematical modeling of neuronal connexin-36 channels.
En: "BBVA Workshop on recent advances in bioinformatics and neuroscience", 09/06/2015 - 11/06/2015, MADRID, SPAIN. p. 1.
Descripción
| Título: | Mathematical modeling of neuronal connexin-36 channels |
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| Autor/es: |
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| Tipo de Documento: | Ponencia en Congreso o Jornada (Póster) |
| Título del Evento: | BBVA Workshop on recent advances in bioinformatics and neuroscience |
| Fechas del Evento: | 09/06/2015 - 11/06/2015 |
| Lugar del Evento: | MADRID, SPAIN |
| Título del Libro: | BBVA Workshop on recent advances in bioinformatics and neuroscience |
| Fecha: | 2015 |
| Materias: | |
| ODS: | |
| Escuela: | Centro de Tecnología Biomédica (CTB) (UPM) |
| Departamento: | Otro |
| Licencias Creative Commons: | Reconocimiento - Sin obra derivada - No comercial |
Resumen
Neurotransmission through electrical synapses play an important role in the spike synchrony among neurons and oscillation of neuron networks. Connexin36 (Cx36) is the principal gap junction protein of electrical synapses between inhibitory interneurons in vertebrates. Coupling strength between coupled neurons is modulated, among other factor, by the voltage difference between cell interiors, termed transjunctional voltage (Vj), in a complex manner; with the Vj gradient junctional conductance of Cx36 channels first increases instantaneously (+ 20% for + 100 mV) and then it decreases slowly to half for a similar range of Vj. The significance of this regulation by voltage, a stimulus always presents and changing, in the firing properties of coupled neurons is unknown.
Más información
| ID de Registro: | 42263 |
|---|---|
| Identificador DC: | https://oa.upm.es/42263/ |
| Identificador OAI: | oai:oa.upm.es:42263 |
| Depositado por: | Memoria Investigacion |
| Depositado el: | 27 Jun 2016 12:02 |
| Ultima Modificación: | 14 May 2024 08:35 |
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