Evaluation of Hyaluronic Acid Dilutions at Different Concentrations Using a Quartz Crystal Resonator (QCR) for the Potential Diagnosis of Arthritic Diseases

Carvajal Ahumada, Luis Armando; Rivera González, Marco Xavier; Herrera Sandoval, Oscar Leonardo y Serrano Olmedo, Jose Javier (2016). Evaluation of Hyaluronic Acid Dilutions at Different Concentrations Using a Quartz Crystal Resonator (QCR) for the Potential Diagnosis of Arthritic Diseases. "Sensors", v. 16 (n. 11); pp. 1-16. ISSN 1424-8220. https://doi.org/10.3390/s16111959.

Descripción

Título: Evaluation of Hyaluronic Acid Dilutions at Different Concentrations Using a Quartz Crystal Resonator (QCR) for the Potential Diagnosis of Arthritic Diseases
Autor/es:
  • Carvajal Ahumada, Luis Armando
  • Rivera González, Marco Xavier
  • Herrera Sandoval, Oscar Leonardo
  • Serrano Olmedo, Jose Javier
Tipo de Documento: Artículo
Título de Revista/Publicación: Sensors
Fecha: Noviembre 2016
Volumen: 16
Materias:
Escuela: Centro de Tecnología Biomédica (CTB) (UPM)
Departamento: Otro
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

The main objective of this article is to demonstrate through experimental means the capacity of the quartz crystal resonator (QCR) to characterize biological samples of aqueous dilutions of hyaluronic acid according to their viscosity and how this capacity may be useful in the potential diagnosis of arthritic diseases. The synovial fluid is viscous due to the presence of hyaluronic acid, synthesized by synovial lining cells (type B), and secreted into the synovial fluid thus making the fluid viscous. In consequence, aqueous dilutions of hyaluronic acid may be used as samples to emulate the synovial fluid. Due to the viscoelastic and pseudo-plastic behavior of hyaluronic acid, it is necessary to use the Rouse model in order to obtain viscosity values comparable with viscometer measures. A Fungilab viscometer (rheometer) was used to obtain reference measures of the viscosity in each sample in order to compare them with the QCR prototype measures.

Más información

ID de Registro: 45021
Identificador DC: http://oa.upm.es/45021/
Identificador OAI: oai:oa.upm.es:45021
Identificador DOI: 10.3390/s16111959
URL Oficial: http://www.mdpi.com/1424-8220/16/11/1959
Depositado por: Memoria Investigacion
Depositado el: 06 Mar 2017 12:41
Ultima Modificación: 26 Abr 2017 18:16
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