Static magnetic field stimulation of the supplementary motor area modulates resting-state activity and motor behavior

Pineda Pardo, José Ángel and Obeso, Ignacio and Guida, Pasqualina and Dileone, Michele and Strange, Bryan A. and Obeso, José A. and Oliviero, A. and Foffani, Guglielmo (2019). Static magnetic field stimulation of the supplementary motor area modulates resting-state activity and motor behavior. "Communications Biology", v. 2 (n. 1); pp. 1-13. ISSN 2399-3642. https://doi.org/10.1038/s42003-019-0643-8.

Description

Title: Static magnetic field stimulation of the supplementary motor area modulates resting-state activity and motor behavior
Author/s:
  • Pineda Pardo, José Ángel
  • Obeso, Ignacio
  • Guida, Pasqualina
  • Dileone, Michele
  • Strange, Bryan A.
  • Obeso, José A.
  • Oliviero, A.
  • Foffani, Guglielmo
Item Type: Article
Título de Revista/Publicación: Communications Biology
Date: 31 October 2019
ISSN: 2399-3642
Volume: 2
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Tecnología Fotónica y Bioingeniería
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Focal application of a strong static magnetic field over the human scalp induces measurable local changes in brain function. Whether it also induces distant effects across the brain and how these local and distant effects collectively affect motor behavior remains unclear. Here we applied transcranial static magnetic field stimulation (tSMS) over the supplementary motor area (SMA) in healthy subjects. At a behavioral level, tSMS increased the time to initiate movement while decreasing errors in choice reaction-time tasks. At a functional level, tSMS increased SMA resting-state fMRI activity and bilateral functional connectivity between the SMA and both the paracentral lobule and the lateral frontotemporal cortex, including the inferior frontal gyrus. These results suggest that tSMS over the SMA can induce behavioral aftereffects associated with modulation of both local and distant functionally-connected cortical circuits involved in the control of speed-accuracy tradeoffs, thus offering a promising protocol for cognitive and clinical research.

Funding Projects

TypeCodeAcronymLeaderTitle
Government of SpainSAF2016-80647-RUnspecifiedUnspecifiedEstimulación cerebral no invasiva con campos magnéticos estáticos : transferiendo la estimulación transcraneal desde el laboratorio al paciente
Government of SpainSAF2017-86246-RUnspecifiedUnspecifiedEstimulación transcraneal por campo magnético estático en la enfermedad de Parkinson
Government of SpainFJCI-2015-2509UnspecifiedUnspecifiedUnspecified

More information

Item ID: 63169
DC Identifier: http://oa.upm.es/63169/
OAI Identifier: oai:oa.upm.es:63169
DOI: 10.1038/s42003-019-0643-8
Official URL: https://www.nature.com/articles/s42003-019-0643-8
Deposited by: Memoria Investigacion
Deposited on: 26 Sep 2020 07:54
Last Modified: 26 Sep 2020 07:54
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