Automated detection of neutropenia using noninvasive video microscopy of superficial capillaries

Pablo Trinidad, Alberto and Butterworth, Ian and Ledesma Carbayo, Maria Jesus and Vettenburg, Tom and Sánchez Ferro, Álvaro and Soenksen, Luis and Durr, Nicholas J. and Muñoz Barrutia, Arrate and Cerrato, Carolina and Humala, Karem and Fabra Urdiol, Marta and Río, Candice del and Valles, Betsy and Chen, Yi-Bin and Hochberg, Ephraim P. and Castro González, Carlos and Bourquard ., Aurélien (2019). Automated detection of neutropenia using noninvasive video microscopy of superficial capillaries. "American Journal of Hematology", v. 94 (n. 8); pp.. ISSN 0361-8609. https://doi.org/10.1002/ajh.25516.

Description

Title: Automated detection of neutropenia using noninvasive video microscopy of superficial capillaries
Author/s:
  • Pablo Trinidad, Alberto
  • Butterworth, Ian
  • Ledesma Carbayo, Maria Jesus
  • Vettenburg, Tom
  • Sánchez Ferro, Álvaro
  • Soenksen, Luis
  • Durr, Nicholas J.
  • Muñoz Barrutia, Arrate
  • Cerrato, Carolina
  • Humala, Karem
  • Fabra Urdiol, Marta
  • Río, Candice del
  • Valles, Betsy
  • Chen, Yi-Bin
  • Hochberg, Ephraim P.
  • Castro González, Carlos
  • Bourquard ., Aurélien
Item Type: Article
Título de Revista/Publicación: American Journal of Hematology
Date: August 2019
ISSN: 0361-8609
Volume: 94
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Cancer patients undergoing cytotoxic chemotherapy are at elevated risk of developing serious infections.1 The risk of developing these infections increases when white blood cell (WBC) counts, particularly the absolute neutrophil counts (ANC), are reduced. This reduction in neutrophil counts, the most abundant white-blood-cell subtype, is referred to as neutropenia, with these infection episodes termed febrile neutropenia (FN). Patients have a high risk of developing FN during sustained severe neutropenia1 (ANC < 500/μL), which is a common side effect of cytotoxic chemotherapies. FN occurs frequently, currently in approximately one in six of all chemotherapy patients,2 and it is associated with a high rate of mortality,3 where 11% of patients die after one or several hospitalizations.4,5 In the United States alone, the associated cost due to such hospitalizations accounts for $2.7B dollars annually,2 contributing to up to 40% of the total cost of cancer treatments.

Funding Projects

TypeCodeAcronymLeaderTitle
FP7291820MVISIONFUNDACION PARA EL CONOCIMIENTO MADRIMASDMVISION
Madrid Regional GovernmentUnspecifiedMadrid–MIT M+Visión ConsortiumUnspecifiedUnspecified

More information

Item ID: 64276
DC Identifier: http://oa.upm.es/64276/
OAI Identifier: oai:oa.upm.es:64276
DOI: 10.1002/ajh.25516
Official URL: https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.25516
Deposited by: Memoria Investigacion
Deposited on: 19 Dec 2020 08:49
Last Modified: 19 Dec 2020 08:49
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