Telomeres: an organized string linking plants and mammals

Di Pietro, Edison ORCID: https://orcid.org/0009-0000-5751-6129, Burla, Romina ORCID: https://orcid.org/0000-0002-5640-4464, La Torre, Mattia ORCID: https://orcid.org/0000-0002-1178-6948, González García, María de la Paz ORCID: https://orcid.org/0000-0002-3739-3368, Dello Ioio, Raffaele ORCID: https://orcid.org/0000-0001-8679-9412 and Saggio, Isabella ORCID: https://orcid.org/0000-0002-9497-7415 (2024). Telomeres: an organized string linking plants and mammals. "Biology Direct", v. 19 ; p. 119. ISSN 1745-6150. https://doi.org/10.1186/s13062-024-00558-y.

Descripción

Título: Telomeres: an organized string linking plants and mammals
Autor/es:
Tipo de Documento: Artículo
Título de Revista/Publicación: Biology Direct
Fecha: 20 Noviembre 2024
ISSN: 1745-6150
Volumen: 19
Materias:
ODS:
Palabras Clave Informales: Telomeres, Stem cells, Niche, Shelterin, Aging, Lifespan, Mice, Humans, Plants, Epigenetics
Escuela: E.T.S. de Ingeniería Agronómica, Alimentaria y de Biosistemas (UPM)
Departamento: Biotecnología - Biología Vegetal
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

Texto completo

[thumbnail of 10270974.pdf] PDF (Portable Document Format) - Se necesita un visor de ficheros PDF, como GSview, Xpdf o Adobe Acrobat Reader
Descargar (6MB)

Resumen

Telomeres are pivotal determinants of cell stemness, organismal aging, and lifespan. Herein, we examined similarities in telomeres of Arabidopsis thaliana, mice, and humans. We report the common traits, which include their composition in multimers of TTAGGG sequences and their protection by specialized proteins. Moreover, given the link between telomeres, on the one hand, and cell proliferation and stemness on the other, we discuss the counterintuitive convergence between plants and mammals in this regard, focusing on the impact of niches on cell stemness. Finally, we suggest that tackling the study of telomere function and cell stemness by taking into consideration both plants and mammals can aid in the understanding of interconnections and contribute to research focusing on aging and organismal lifespan determinants.

Proyectos asociados

Tipo
Código
Acrónimo
Responsable
Título
Gobierno de España
PID2022-140719NB-I00
Sin especificar
Sin especificar
Sin especificar

Más información

ID de Registro: 93919
Identificador DC: https://oa.upm.es/93919/
Identificador OAI: oai:oa.upm.es:93919
URL Portal Científico: https://portalcientifico.upm.es/es/ipublic/item/10270974
Identificador DOI: 10.1186/s13062-024-00558-y
URL Oficial: https://link.springer.com/article/10.1186/s13062-0...
Depositado por: iMarina Portal Científico
Depositado el: 13 Feb 2026 17:20
Ultima Modificación: 13 Feb 2026 17:20